Healing The Erosions In Your Esophagus With Nexium
Heather Colman
Nexium has come as a wonderful relief in treating heartburn in
acid reflux disorders. Acids are released in the stomach for
digestion of food. When some of this acid persistently flows back
into the food tube, the esophagus, its lining get damaged leading
to a condition known as erosive esophagitis. You suffer from
persistent heartburn. Changing diets also do not help. Just one
pill a day of Nexium can relieve you of the pain and agony of
severe and continuous heartburn.
Nexium generically is esomeprazole magnesium and is available as
a Delayed- Release capsule for oral administration. If you are
having typical heartburn symptoms on 2 or more days per week in
spite of treatment and diet change, you need to consult a doctor
to find out whether you are suffering from acid reflux disease.
Only a Doctor can confirm whether the lining of your esophagus
has been damaged due to back flow of stomach acids in this food
pipe for frequent relaxes of the lower esophageal sphincter. If
this lining has been eroded, you have the condition known as
erosive esophagitis and your heartburn is due to this cause.
Nexium administration can heal these erosions in the esophagus in
4 to 8 weeks. However, results may vary depending on your age and
extent of damage. Nexium therapy is often associated with minor
side effects. Over 8500 patients in the United States and over
6500 patients in Europe and Canada underwent clinical trials to
ascertain the safety of Nexium. Near about 3000 patients were
studied in long-term trials. The tolerance, both in short-term
and long-term trials were found to be fairly satisfactory. Nexium
was administered in various doses in patients with confirmed
erosive esophagitis. For all dosage levels, some headache (+/-
1%) was reported. The intensity varied according to the level of
the dose. Very mild diarrhea was also noticed but it had no
relation with dosage level. Some nausea, flatulence, abdominal
pain and dry mouth symptoms were reported in the trials. However,
similar symptoms also appear in patients on omeprazole medication
for stomach disorders.
Marketed by AstraZeneca Pharmaceuticals, Nexium is a proton pump
inhibitor (PPI) and is well indicated for the treatment of
heartburn in erosive esophagitis and other symptoms associated
with GERD. It suppresses gastric acid secretion in the stomach by
blocking the final step in acid production. Nexium can also be
prescribed with antibiotics for eradication of H.Pylori that
reduces the risk of duodenal ulcer recurrence. A very recent
study conducted with more than 1000 patients with erosive
esophagitis show Nexium (esomeprazole) to be more effective in
healing the disorder than lansoprazole (Prevacid). Results of
this study has been published in July, 2006 issue of Clinical
Gastroenterology and Hepatology. According to Dr. Kenneth
DeVault, MD, Director of Gastrointestinal Research, Mayo Clinic
College of Medicine, Jacksonville, Florida, and the lead study
investigator, "Esomeprazole therapy was able to control both
mucosal damage and reflux symptoms" in healing the erosions in
the esophagus.
Disclaimer - The information presented here should not be
interpreted as or substituted for medical advice. Please talk to
a qualified professional for more information about Nexium.
Copyright © 2006, Heather Colman. Find more Protonix resources
at: http://www.protonix-center.info
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